Alcohol-related peripheral neuropathy: a systematic review and meta-analysis

Epidermal nerve fibre density was assessed in two studies, both of which supported decremental nerve fibre density distally in the lower limb, anecdotally supportive of a length-dependent pattern 53, 63. The medical community has recognized that addiction is a disease and some people are predisposed to it. As a result, it is usually necessary to get medical help to manage alcohol use disorder. Since nutritional deficiencies are partly to blame for alcoholic neuropathy. To combat these deficiencies, supplementation with vitamin B12, folate, vitamin E, and thiamine may be recommended.

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• Alcohol consumption is one of several lifestyle factors that can contribute to joint pain.
• Eventually, it can cause a loss of nerve function, primarily in the extremities.
• Besides alcohol consumption, other causes of neuropathy may include non-alcohol-related nutritional imbalances, metabolic issues, infections, traumatic injuries, inherited, and exposure to toxins.
• Excessive drinking can be especially dangerous for people with diabetes, because they could develop hypoglycemic unawareness.
• The main symptoms of ALN include dysesthesia, paresthesia, numbness, and pain in the lower extremities which progressively reach higher parts of the body 114,115,116,117.
• A poor diet that lacks vitamin B12 or folate can result in peripheral neuropathy.
• Anything from sniffing paint, glue, or various inhalants can have such an effect.

We’ll explain all of these risks in a moment, but this table can help you understand the long-term and short-term cardiovascular risks drinking can cause. Excessive alcohol consumption can have a systemic impact on the human body, affecting everything from your cardiovascular system to your digestion. These issues can lead to long-term health conditions and can impact every aspect of your life. Excessive alcohol consumption is just one of several potential causes of neuropathy.

What are the symptoms of alcoholic neuropathy?

It also appears https://ecosoberhouse.com/ that some people may inherit an increased risk of developing alcoholic liver disease. It’s critical to understand the effects of alcohol on your cardiovascular function. Heavy drinking can lead to a range of issues that could be long-term and potentially life-threatening.

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As the condition progresses, these sensations can lead to pain, muscle weakness, and even muscle atrophy. The nerve alcohol neuropathy stages damage can also affect autonomic functions, leading to problems with blood pressure regulation, bowel and bladder control, and sexual function. These physical symptoms, combined with the psychological impact of chronic pain and mobility issues, can lead to depression, anxiety, and social withdrawal, further diminishing life quality. The prognosis for alcoholic neuropathy depends on various factors, including the extent of nerve damage and the individual’s commitment to avoiding alcohol and adhering to treatment plans.

• Beyond that, your physician will likely prescribe you a variety of different supplements, most likely thiamine and folic acid.
• This deficiency, combined with the toxic effects of alcohol on nerve cells, precipitates the development of neuropathic symptoms.
• Vitamin B12 is essential for nerve regeneration, nerve cell survival, and myelin sheath maintenance.
• A person acting with a combination of heavily impaired judgment, poor motor function, and significant memory lapses is a potential danger to themselves and those around them.
• A doctor may also want to test the functioning of the kidneys, liver, and thyroid.

It was shown that patients with liver cirrhosis (regardless of its etiology) present dysfunctions in ANS, primarily within the vagus nerve 170. There is a strong correlation between AAN and Child-Pugh scale which suggests that liver cirrhosis progression is related to impairments in ANS 172. Alcohol-abusing patients with liver cirrhosis and vagus nerve neuropathy are at higher risk of a sudden death compared to patients without impairments within the nervous system 173, 174. alcoholism During the initial stages of ALN, the disease may appear asymptomatic and demonstrable only on electroneurographic investigation 71, 111, 112.